Meat Lovers Pizza Casserole Recipe
Meat Lovers Pizza Casserole: The Ultimate Comfort Food Delight (Hearty Meat Lovers Pizza Casserole Recipe)
Are you ready to elevate your weekend meals with a dish that’s as satisfying as a cozy hug? Say hello to the Meat Lovers Pizza Casserole, where every forkful is a celebration of irresistible flavors! This dreamy casserole is layered with succulent beef, zesty sausage, and a medley of gooey cheeses, all wrapped up in a delightful pasta embrace. Whether you’re hosting a gathering or simply craving a comforting homemade feast, this casserole is bound to steal the show!

Why You’ll Love This Recipe
You’re just a few steps away from a meal that’s packed with flavor and smiles!
– Big, Bold Flavors: Each bite bursts with the rich, savory taste of meats and cheeses, making your taste buds dance with joy!
– Crowd-Pleaser: Perfect for family gatherings or potlucks, this dish will leave your guests asking for seconds (and thirds).
– Flexible & Fast: Quick to prepare and easy to customize, this casserole is your new weeknight hero!
– Make-Ahead Magic: Assemble it ahead of time and pop it in the oven when you’re ready to feast!
Ingredients You’ll Need
Let’s gather the stars of this mouthwatering show! This recipe is all about creating layers of flavor and texture, so pay special attention to those savory meats and creamy cheeses—you won’t regret it!

– 12 ounces penne or rotini pasta
– 1 pound ground beef
– 1/2 pound crumbled Italian sausage
– 1/2 cup pepperoni slices
– 1/2 cup cooked and crumbled turkey bacon
– 2 cups marinara sauce or pizza sauce
– 1 teaspoon Italian seasoning
– 2 cups shredded mozzarella cheese
– 1/2 cup shredded cheddar cheese
– 1/4 cup grated Parmesan cheese
– 1/2 teaspoon garlic powder
– 1/2 teaspoon optional red pepper flakes
*Note: You’ll find the complete list of ingredients, along with their exact measurements, in the printable recipe card at the bottom of this post.*
Variations
The beauty of the Meat Lovers Pizza Casserole lies in its versatility! Feel free to get creative with these fun variations:
– Go Gluten-Free: Swap out regular pasta for gluten-free pasta to make this dish suitable for gluten-sensitive diets.
– Add Extra Protein: Throw in some cooked grilled chicken or crispy bacon for an even heartier meal!
– Make it Spicier: Add some jalapeños or extra red pepper flakes for a fiery kick!
– Swap the Dressing: Try BBQ sauce instead of marinara for a smoky twist.
– Cheese it Up: Experiment with a variety of cheeses, like provolone or gouda, for a unique cheesy experience.
How to Make Meat Lovers Pizza Casserole Recipe
Ready to dive into this cheesy wonder? Let’s get cooking!
Step 1: Cook and Cool the Pasta
Bring a pot of salted water to a boil, then add the penne or rotini. Cook according to package instructions until al dente. Drain the pasta and set it aside to cool slightly.
Step 2: Sizzle the Meats
In a large skillet over medium heat, combine the ground beef and crumbled Italian sausage. Cook them until they’re beautifully browned and fully cooked, making sure to drain any excess fat for a cleaner finish.
Step 3: Preheat the Oven
While the meats are sizzling, preheat your oven to 375°F (190°C). This is where the magic happens!
Step 4: Combine the Ingredients
In a large mixing bowl, combine the cooked pasta, meat mixture, pepperoni, turkey bacon, marinara sauce, Italian seasoning, garlic powder, and optional red pepper flakes. Mix everything together until every piece is coated in that aromatic goodness.
Step 5: Assemble the Casserole
Pour the glorious mixture into a greased 9×13-inch baking dish. Then, sprinkle the shredded mozzarella, cheddar, and Parmesan cheeses generously over the top.
Step 6: Bake to Perfection
Pop the casserole in the preheated oven and bake for 20 to 25 minutes, or until the cheese is melting and bubbly, creating a golden crust that beckons you to dive right in!
Step 7: Cool & Serve
Allow your masterpiece to cool for a few minutes before slicing it up. Get ready for the oohs and aahs as you serve this delightful dish!
Pro Tips for Making Meat Lovers Pizza Casserole Recipe
– Don’t Skimp on Seasoning: Adding Italian seasoning and garlic powder enhances the overall flavor—don’t skip it!
– Layer Smart: Ensure an even distribution of meat and cheese throughout the casserole for every bite to be equally delicious.
– Let It Rest: Allowing the casserole to sit for a few minutes after baking helps it set, making it easier to slice.
How to Serve Meat Lovers Pizza Casserole Recipe
Garnishes
Sprinkle some fresh basil or parsley on top for a pop of color and an added layer of flavor!
Side Dishes
Pair this hearty casserole with a light side salad or some garlic bread to balance out the richness.
Creative Ways to Present
Serve individual portions in ramekins for fun, personalized servings, or set up a buffet-style spread for a casual family gathering.
Make Ahead and Storage
Storing Leftovers
Store any leftovers in an airtight container in the fridge for up to 3-4 days. Just reheat and enjoy!
Freezing
This casserole freezes beautifully! Assemble and freeze before baking. When ready to enjoy, just thaw overnight in the fridge and bake as directed.
Reheating
For the best results, reheat individual servings in the microwave or warm the whole dish in the oven until bubbly.
FAQs
Can I use a different type of meat?
Absolutely! Feel free to mix and match your favorite meats based on what you have on hand.
Is this recipe spicy?
It’s not inherently spicy, but you can easily make it spicy by adding red pepper flakes or jalapeños.
How do I make this gluten-free?
Simply substitute regular pasta with gluten-free pasta, and you’re good to go!
Can I prepare this in advance?
Yes! You can assemble the casserole ahead of time and refrigerate it until you’re ready to bake.
Final Thoughts
The Meat Lovers Pizza Casserole is not only a hearty meal but also a delightful experience that brings people together around the table. Its cheesy, meaty goodness is sure to please even the pickiest eaters, making it a staple in your recipe repertoire. So roll up your sleeves, gather your ingredients, and get ready to enjoy a deliciously fulfilling dish that’s easy to make and impossible to resist! Happy cooking!
Meat Lovers Pizza Casserole Recipe
Indulge in the ultimate comfort food with this Meat Lovers Pizza Casserole, a deliciously hearty dish that combines all your favorite pizza toppings into one easy-to-make casserole. Perfect for family gatherings or cozy weekends, this dish is packed with flavor and sure to satisfy even the hungriest of appetites. With layers of pasta, savory meats, and gooey cheese, this cheesy delight will become a staple in your home.
- Prep Time: 15 minutes
- Cook Time: 25 minutes
- Total Time: 40 minutes
- Yield: Serves 8
- Category: Main Dish
- Method: Baking
- Cuisine: Italian-American
Ingredients
- 12 ounces penne or rotini pasta
- 1 pound ground beef
- 1/2 pound crumbled Italian sausage
- 1/2 cup pepperoni slices
- 1/2 cup cooked and crumbled turkey bacon
- 2 cups marinara or pizza sauce
- 1 teaspoon Italian seasoning
- 2 cups shredded mozzarella cheese
- 1/2 cup shredded cheddar cheese
- 1/4 cup grated Parmesan cheese
- 1/2 teaspoon garlic powder
- 1/2 teaspoon optional red pepper flakes
Instructions
- Preheat oven to 375°F (190°C). Cook pasta according to package instructions; drain and set aside.
- In a skillet, brown the ground beef and Italian sausage over medium heat. Drain excess fat.
- In a large bowl, mix cooked pasta, meat mixture, pepperoni, turkey bacon, marinara sauce, Italian seasoning, garlic powder, and red pepper flakes (if using).
- Pour into a greased 9×13-inch baking dish. Top with mozzarella, cheddar, and Parmesan cheese.
- Bake for 20-25 minutes until cheese is melted and bubbly. Cool slightly before serving.
Nutrition
- Serving Size: 1 slice (about 130g)
- Calories: 470
- Sugar: 6g
- Sodium: 890mg
- Fat: 30g
- Saturated Fat: 13g
- Unsaturated Fat: 14g
- Trans Fat: 0g
- Carbohydrates: 32g
- Fiber: 2g
- Protein: 28g
- Cholesterol: 80mg